Suntheanine directly stimulates the production of alpha brain waves, a state often achieved by meditation. It is one of deep relaxation and mental alertness.
Suntheanine is absorbed in the small intestine via a sodium-coupled active transport process and crosses the blood-brain barrier where it is absorbed into the brain in a dose-dependent manner. Suntheanine may compete for absorption in the intestinal tract and brain with amino acids found in the methionine group, including isoleucine, leucine and valine. Concentrations of other amino acids are unchanged by Suntheanine.
Suntheanine plays a role in the formation of the inhibitory neurotransmitter GABA and increases dopamine release through modulation of glycine and AMPA receptors. Suntheanine promotes a relaxation and excitatory inhibition effect without leading to drowsiness.*